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Hormonal Imbalance Detected
Recommended treatment period: 3 Months

Your Hormonal Status

Based on Your Quiz Results

Estrogen
Promotes belly fat accumulation when low
Critically Low
Progesterone
Disrupts sleep, mood & cravings when low
Critically Low
Cortisol
Blocks fat-burning when elevated
Too High
Your hormones can naturally rebalance within 3 months.

Your Weight Loss Outlook

Today Day 60+
With Purefemm
With a Diet Alone
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(1,293 Reviews)

Menopause Complex+

Join thousands of women reclaiming their bodies during menopause — with just 2 capsules a day.

Effective Support For

Weight Gain

Sleep Problems

Bloating

Mood Swings

Hot Flashes

Joint Discomfort

Cravings

Vaginal Dryness

What Women Report

Based on customer feedback & internal data. Individual results may vary.

✓
Weeks 1–2
94 % report more energy and a more stable mood.
First signs of hormonal stabilization & fewer "energy crashes."
✓
Weeks 3–4
92 % report better sleep and fewer hot flashes.
Many describe calmer nights & less night sweating.
✓
Weeks 5–6
90 % report cravings and bloating noticeably ease up.
More stable blood sugar & less of that persistent "menopause belly" feeling.
✓
Weeks 6–8
89 % find it easier to manage their weight — especially around the belly.
No crash effect — just gradual, steady metabolic reactivation.
Ordered 402 times in the last 24 hours

1-Month Supply

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1-month supply

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$59,95

$49.95 per bottle

30 SERVINGS

$1,33/Day

1 BOTTLE

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3-Month Supply

Optimal for visible, lasting results

3-Monats-Vorrat

Optimal for visible, lasting results

$59,95

$29,98 per bottle

$0,99/DAY

90 Servings

3 BOTTLES

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+ Free Bonuses Value: $150
  • Free E-Book: 6 Secrets About Menopause
  • 15% off your next order
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6-Month Supply

For maximum, long-lasting results

6-Monats-Vorrat

For maximum, long-lasting results

$59,95

$21,67 per bottle

$0,83/Day

180 Servings

6 BOTTLES

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+ Free Bonuses Value: $150
  • Free E-Book: 6 Secrets About Menopause
  • 15% off your next order
  • Free Priority Shipping 3–5 Business Days
  • 24/7 VIP Support

100-Day Money-Back Guarantee

1-Month Supply

Perfect for trying it out

1-month supply

Ideal solution for trying out

$59,95

$49.95 per bottle

30 SERVINGS

$1,33/Day

1 BOTTLE

ORDER NOW

No bonus gifts included.
Save more with 3 or 6 months.

100-Day Money-Back Guarantee

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Customer Transformations

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What Experts Say

About Us

At Purefemm, we use carefully selected ingredients that are science-backed and meet the highest standards of purity and efficacy.

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Vegan

GMO-Free

Hormone

Free

Ships from the

US

Expert

Formulated

Clinically

Studied

13 clinically studied ingredients

that support hormonal balance. Click any ingredient to learn more.

Simply click on each ingredient to learn more about its benefits, research, and how it's used.

View All ingredients

Bifidobacterium

lactis B420®

Supports gut microbiome balance, promotes digestion and immunity, and strengthens overall well-being during menopause.*

Ashwagandha

KSM-66®

Helps regulate elevated cortisol levels, supports emotional balance, and promotes better sleep during menopause.*

Sage

Leaf Extract

Supports natural temperature regulation, may help reduce hot flashes, and promotes inner calm.*

Lemon Balm

Extract

A traditional medicinal herb with a long history of use — part of our plant-based formula.

Green Tea

Extract

Promotes thermogenesis, supports energy metabolism, and contributes to an active, healthy metabolism.*

Chromium

Helps stabilize blood sugar levels, reduces cravings, and supports consistent energy throughout the day.*

Menopause Complex⁺ Helps Women of All Ages

Reclaim Their Balance

Flatter Belly

Hormonal changes during menopause actively promote stubborn belly fat. Menopause Complex⁺ supports your metabolism & blood sugar balance* — so you can feel comfortable in your body and your clothes again.

Hormonal Balance*

Hot flashes, mood swings, sleep problems, and brain fog all stem from fluctuating hormones. Our formula helps stabilize that balance* — for calmer nights, a clearer head, and more consistent energy throughout the day.

Lighter, Easier Days

Digestive issues, bloating, and water retention are common in menopause. Probiotics & plant extracts help soothe digestion and promote a lighter, more comfortable feeling in your body.*

Try It Risk- Free with Our 100 Day Money Back Guarantee!

Science, doctors, and our customers all agree: Menopause Complex⁺ works! That's why we offer a 100-day, completely risk-free money-back guarantee.


If, for any reason, you don't see any results — or you simply change your mind — you'll receive a full refund. In other words: you only pay if Purefemm truly delivers for you.

Verified Customer

Angela O.

I was mentally and physically at my lowest. I'd gained 26 lbs during menopause and just didn't feel like myself anymore. After one month on Menopause Complex⁺ I could already feel something shifting — not just on the scale, but in my head too. After 6 months I'm down 20 lbs and feel like my old self again. It was a long road, but it was completely worth it.

100,000+ women say yes to
Menopause Complex+!

Even doctors recommend it to their patients.

Verified Customer

Hildegard P.

I'm normally a pretty happy person, but for months I was just in a constant low. And the weight kept creeping up no matter what I did. Since I started Menopause Complex⁺ my mood has completely shifted — and I've also lost 11 lbs without even really trying. My belly is flatter and I have energy again. I finally feel like myself.

Verified Customer

Sarah Z.

I was super skeptical, but tried it out of desperation. Since menopause I felt like I was gaining every single month, and my belly just kept getting bigger. After two weeks I actually noticed a difference — my belly looked flatter, I didn't feel so bloated anymore. Eight weeks in, I'm down 13 lbs. I'm honestly shocked it worked. Sticking with it.

  PUREFEMM Others
Comprehensive 3-phase system
Clinically dosed ingredients
Mood, sleep & stress support
No fillers & unnecessary additives
100% plant-based & vegan
Free from GMO, gluten & synthetic hormones
No artificial sweeteners
100-Day Money-Back Guarantee
35+ clinical studies support our ingredients

What People Are Asking

Transparency & Science

Clinical Studies & Sources

Every ingredient, claim, and mechanism in Menopause Complex⁺ is supported by peer-reviewed research. Here you'll find all the studies.

35+
Cited Studies
14
Clinically Studied Ingredients
6
Meta-Analysiss
15.000+
Study Participants
Mechanisms of Action & Product Claims
🦴
Estrogen Deficiency & Joint Pain
Mechanism: Estrogen loss → reduced joint lubrication → joint pain | 4 Studies
4 Studies ▾
WHI · RCT · n=10,739
Estrogen Alone and Joint Symptoms in the Women's Health Initiative Randomized Trial
The largest study on this topic (10,739 postmenopausal women): estrogen monotherapy led to a significant, sustained reduction in joint pain frequency vs. placebo — demonstrated at 1, 3, and 6 years. 77% of women reported joint pain at baseline.
Chlebowski RT et al. · Menopause, 2013/2018 · PubMed Central →
Review · 2025
Joint Pain and Menopause
Current review: 70% of women during menopause report musculoskeletal symptoms. Estrogen receptors are found in bones, articular cartilage, synovial membranes, and muscles — estrogen deficiency affects the entire musculoskeletal system.
PMC Review · 2025 · PubMed Central →
Narratives Review · 2025
The Intersection of Aging and Estrogen in Osteoarthritis
Estrogen promotes proteoglycan and collagen synthesis in chondrocytes, inhibits inflammation, and protects cartilage. Estrogen deficiency after menopause accelerates cartilage degeneration and significantly increases osteoarthritis risk.
npj Women's Health, 2025 · Nature →
Narrative Review · 2025
Knee Osteoarthritis and Menopausal Hormone Therapy in Postmenopausal Women
Data from 4,766 postmenopausal women: knee osteoarthritis prevalence was 30% lower in women on hormone therapy (OR 0.70, 95% CI 0.50–0.99) — direct evidence of estrogen's protective effect on joints.
Jung JH et al. · Menopause, 2019 · PubMed →
⚖️
Cortisol, Menopause Belly & Weight Gain
Claim: Hormonal imbalance → visceral fat storage → metabolic slowdown | 3 Studies
3 Studies ▾
Review · International Menopause Society
Understanding Weight Gain at Menopause
Official IMS review: hormonal changes during perimenopause lead to increased total body fat and greater abdominal fat storage. Estrogen and estrogen-progestogen therapy reduce fat mass and improve insulin sensitivity.
Davis SR et al. · Climacteric, 2012 · PubMed →
Narratives Review · 2021
Weight Regulation in Menopause
Women gain an average of 1 lb per year during menopause; 20% gain more than 11 lbs. Menopause shifts fat storage from gynoid (hips/thighs) to android (abdominal) distribution. Declining estrogen and SHBG levels increase metabolic risk.
Chopra S et al. · Cureus, 2021 · PubMed Central →
Mechanism · Cortisol Axis
Cortisol, Menopause and Visceral Fat Accumulation
Chronically elevated cortisol during perimenopause stimulates insulin release → triglyceride storage in belly fat. Visceral fat has 4× more cortisol receptors than subcutaneous fat. Estrogen normally acts anti-cortisol — that protection disappears with menopause.
Based on: Epel et al. (Yale), WHI-Analysen, Davis et al. · Review →
🌡️
Hormone Fluctuations → Symptom Cascade
Claim: Fluctuating hormones → hot flashes, sleep disruption, mood swings, brain fog
2 Studies ▾
Review · Roles of HRT
Roles of Hormone Replacement Therapy and Menopause on Osteoarthritis and Cardiovascular Disease Outcomes
Menopause represents a significant physiological turning point: the rapid decline of estrogen and progesterone leads to complex changes — from vasomotor symptoms to cardiovascular risks to musculoskeletal complaints.
Zhu X et al. · Frontiers in Rehab Sciences, 2022 · PubMed Central →
Narratives Review · 2021
Weight Regulation in Menopause — Hormonal Cascade Effects
Declining estradiol and estrone levels, rising free androgens (via reduced SHBG), and disrupted cortisol rhythms create a metabolic cascade: impaired thermoregulation (hot flashes), sleep disruptions, mood instability, and cognitive impairment.
Chopra S et al. · Cureus, 2021 · PubMed Central →
Ingredient Studies
🦠
Bifidobacterium lactis B420®
Gut microbiome balance · Weight management · Gut barrier
4 Studies ▾
RCT · Double-Blind 6 Month · n=225
Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults
Gold-standard 6-month study: B420 significantly reduced body fat mass, waist circumference (−2.4 cm), and calorie intake (~300 kcal/day less) vs. placebo in overweight adults (BMI 28–34.9).
Stenman LK et al. · EBioMedicine, 2016 · PMC →
Systematic Review
B. animalis subsp. lactis 420 for Metabolic Health: Review of the Research
Comprehensive review of in-vitro, preclinical, and clinical studies: B420 improves gut barrier integrity, promotes Akkermansia muciniphila (associated with lean phenotype), and supports metabolic balance.
Uusitupa HM et al. · Nutrients, 2020 · PMC →
Preclinical
B420 Prevents Weight Gain and Glucose Intolerance in Diet-Induced Obese Mice
B420 prevented weight gain, improved insulin sensitivity, and reduced endotoxemia as well as tissue inflammation in mice fed a high-fat diet.
Stenman LK et al. · Diabetology & Metabolic Syndrome, 2015 · PubMed →
RCT · Post-hoc Analysis
Probiotic or Synbiotic Alters the Gut Microbiota and Metabolism
Short-chain fatty acids (propionic, butyric, and valeric acid) increased significantly — these regulate appetite, gut integrity, and glucose metabolism.
Hibberd AA et al. · Beneficial Microbes, 2018 · Source →
🌿
Ashwagandha KSM-66®
Cortisol · Stress · Menopause symptoms · Sleep · Estradiol | 5 Studies
5 Studies ▾
RCT · Double-Blind 60 Days · n=64
Safety and Efficacy of Ashwagandha Root in Reducing Stress and Anxiety
600 mg/day KSM-66 reduced serum cortisol by 27.9% (vs. 7.9% placebo, p=0.002). Significant improvement on all stress scales. Improved sleep quality, calm, and productivity.
Chandrasekhar K et al. · Indian J Psychol Med, 2012 · PMC →
RCT · Double-Blind 8 Weeks · n=60
Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults
First dose-response study: 600 mg/day significantly reduced cortisol (p<0.0001), and 250 mg/day also reduced cortisol (p<0.05). Sleep quality improved significantly in both groups.
Lopresti AL et al. · Cureus, 2019 · PubMed →
RCT · Double-Blind 8 Weeks · n=100
Effect of Ashwagandha Root Extract on Climacteric Symptoms in Perimenopause
100 perimenopausal women: significant reduction in menopause symptoms, significant estradiol increase (p<0.0001), reduction of FSH (p<0.0001) and LH (p<0.05) vs. placebo.
Gopal S et al. · J Obstet Gynaecol Res, 2021 · PubMed →
RCT · Double-Blind 56 Days · n=60
Efficacy and Safety of Ashwagandha Root Extract for Managing Menopausal Symptoms
Women aged 45–55: Significant improvement across all MRS domains (p<0.0001), estradiol and progesterone increased, while LH and FSH decreased. Fewer hot flashes and improved quality of life.
Shukla A et al. · Front Reprod Health, 2025 · PMC →
RCT · Double-Blind 24 Weeks · Postmenopausal Women
Ashwagandha and Shatavari Extracts Reduce Menopause Symptoms, Vascular Dysfunction, and Bone Resorption
24-week study (ages 40–55): Dose-dependent reduction in menopause symptoms, improved vascular function, reduced bone resorption markers, and lower inflammatory markers.
Pingali U et al. · J Menopausal Med, 2025 · PMC →
🍃
Sage Extract
Hot Flashes · Night Sweats · Temperature Regulation
4 Studies ▾
Clinical Study8 Weeks · n=71
First Time Proof of Sage's Tolerability and Efficacy in Menopausal Women with Hot Flushes
First clinical study of sage in menopause: 50% reduction after 4 weeks, 64% after 8 weeks. Conducted in 8 Swiss practices, with good tolerability.
Bommer S, Klein P, Suter A · Adv Therapy, 2011 · PubMed →
RCT · Double-Blind8 Weeks · n=100
Effect of Salvia Officinalis Tablet on Hot Flashes, Night Sweats, and Estradiol Hormone
100 postmenopausal women (300 mg/day): Significant reduction in the frequency, severity, and duration of hot flashes and night sweats.
Dadfar F, Bamdad K · Int J Med Res & Health Sci, 2019 · PDF →
RCT · Double-Blind
Effectiveness of Menosan® Salvia officinalis in the Treatment of a Wide Spectrum of Menopausal Complaints
Placebo-controlled: Significant improvement across a wide range of menopausal symptoms — hot flashes, sleep, and mood.
Wilfried D et al. · Heliyon, 2021 · ScienceDirect →
Meta-Analysis
The Effect of Salvia Officinalis on Hot Flashes: Systematic Review and Meta-Analysis
Meta-analysis of multiple RCTs confirms: sage significantly reduces hot flashes in terms of frequency, severity, and duration.
Moradi M et al. · IJCBNM, 2023 · PMC →
🍵
Green Tea Extract (EGCG)
Thermogenesis · Fat Oxidation · Metabolic Activation
4 Studies ▾
RCT · Double-Blind12 Weeks · n=102
Therapeutic Effect of High-Dose Green Tea Extract on Weight Reduction
102 women with central obesity: EGCG (856.8 mg/day) led to significant weight loss (p=0.025), BMI reduction (p=0.018), and waist circumference reduction (p=0.023). Ghrelin decreased, adiponectin increased.
Chen IJ et al. · Clinical Nutrition, 2016 · ScienceDirect →
Syst. Review · 15 Studies
Effect of Green Tea Catechins on Resting Metabolic Rate, Energy Expenditure and Respiratory Quotient
15 studies (n=499): Green tea catechins showed positive effects on fat oxidation and energy expenditure. EGCG stimulates thermogenesis and influences body weight and composition.
Reale M et al. · Nutrients, 2021 · PMC →
Mechanism
Green Tea Extract Thermogenesis by EGCG Inhibition of COMT
EGCG inhibits Catechol-O-Methyltransferase (COMT), the enzyme that breaks down norepinephrine, thereby prolonging sympathetic stimulation of thermogenesis — the key fat-burning mechanism.
Lu H et al. · J Med Food, 2006 · PubMed →
Syst. Review · 10 Studies
Green Tea Induces the Browning of Adipose Tissue
Green tea activates UCP1, PGC-1α, and PRDM16 — key proteins for converting white fat into brown, calorie-burning fat tissue. Fat tissue mass was reduced in all studies.
Santos HO et al. · Obesities, 2023 · MDPI →
⚡
Chromium (Chromium Picolinate)
Blood Sugar · Cravings · Insulin Sensitivity
4 Studies ▾
RCT · Double-Blind8 Weeks · n=42
Effects of Chromium Picolinate on Food Intake and Satiety
42 overweight women with carbohydrate cravings: 1,000 µg CrPic/day significantly reduced hunger, fat cravings, and food intake vs. placebo.
Anton SD et al. · Diabetes Technol Ther, 2008 · PMC →
Meta-Analysis · 25 RCTs
Systematic Review and Meta-Analysis of Chromium Supplementation in Diabetes
25 RCTs: Chromium significantly improved HbA1c (−0.55%) and fasting glucose (−1.15 mmol/L). Chromium picolinate also lowered triglycerides and increased HDL-C.
Suksomboon N et al. · J Clin Pharm Ther, 2014 · PubMed →
Meta-Analysis · 2020
Effects of Chromium Supplementation on Glycemic Control in T2DM Patients
Current meta-analysis confirms: chromium significantly improves glycemic control markers in people with type 2 diabetes. Support for blood sugar regulation.
Asbaghi O et al. · Pharmacol Res, 2020 · PubMed →
RCT · Double-Blind · Pilot6 Months · n=24
Chromium Picolinate for Binge Eating Disorder (BEACh Study)
Fasting glucose decreased significantly in both chromium groups vs. placebo (dose-dependent). 86% of prediabetic participants normalized their HbA1c with chromium.
Brownley KA et al. · J Psychosom Res, 2013 · PMC →
Disclaimer: The studies listed refer to individual ingredients, mechanisms of action, and their isolated effects. Results may vary depending on dosage, study population, and individual factors. Dietary supplements are not a substitute for a balanced diet and a healthy lifestyle. The cited studies do not constitute medical advice. Please always consult a doctor or qualified healthcare professional if you have health-related questions. All sources are publicly available through PubMed, PubMed Central, and the respective scientific journals.